new concerns about using Viagra (sildenafil) in patients taking HIV protease inhibitors

July 1999

There are new concerns about using Viagra (sildenafil) in patients taking HIV protease inhibitors.

One patient on ritonavir and saquinavir had an MI and died...after taking a 25 mg dose of Viagra.

Protease inhibitors slow Viagra metabolism...leading to significantly higher and more prolonged levels.

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