Limit the Dose of Hydroxyzine to 100 mg Per Day in Adults
October 2016
Recent warnings and labeling changes will highlight the risk of QT prolongation and torsades with hydroxyzine.
Most cases are in patients with QT prolongation risk factors...such as a history of QT prolongation or arrhythmias, electrolyte imbalances, or on other QT-prolonging drugs (haloperidol, methadone, etc).
Use alternatives to hydroxyzine in patients at high risk.
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