Compare Nalmefene and Naloxone for Opioid Overdose Reversal

December 2023

New Rx nalmefene nasal spray (Opvee) will join naloxone as an option to reverse opioid overdose.

Both are opioid receptor blockers...with an onset of 3 to 5 minutes.

But nalmefene nasal spray lasts about 6 hours...versus about 2 hours for naloxone nasal spray.

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