Optimize LDL-C Lowering Meds After Acute Coronary Syndrome

June 2025

You’ll get questions about managing cholesterol after acute coronary syndrome (ACS)...due to recent guideline updates.

LDL-C goals. Aim for at least a 50% LDL-C reduction AND an LDL-C less than 70 mg/dL for most patients after ACS.

But think “lower is better” and target an LDL-C under 55 mg/dL for some higher-risk patients, such as those with prior CV events or diabetes.

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